Reiner Siebert Selected Research

Typical Teratoid Rhabdoid Tumor

1/2022	ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance.
1/2021	Transposable element insertion as a mechanism of SMARCB1 inactivation in atypical teratoid/rhabdoid tumor.
9/2014	Synchronous congenital malignant rhabdoid tumor of the orbit and atypical teratoid/rhabdoid tumor--feasibility and efficacy of multimodal therapy in a long-term survivor.
2/2013	High-resolution genomic analysis suggests the absence of recurrent genomic alterations other than SMARCB1 aberrations in atypical teratoid/rhabdoid tumors.
6/2011	Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression.

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Reiner Siebert Research Topics

Disease

72	Neoplasms (Cancer) 06/2022 - 03/2002
48	Lymphoma (Lymphomas) 01/2022 - 02/2002
28	B-Cell Lymphoma (Lymphoma, B Cell) 04/2022 - 10/2003
19	Genetic Translocation (Chromosomal Translocation) 12/2021 - 03/2002
17	Hodgkin Disease (Hodgkin's Disease) 01/2019 - 05/2003
14	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2020 - 06/2006
13	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 10/2020 - 10/2003
13	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2019 - 03/2004
12	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2019 - 11/2005
9	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 06/2022 - 02/2003
9	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 10/2021 - 10/2003
8	Rhabdoid Tumor (Rhabdoid Tumors) 12/2021 - 02/2010
7	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 06/2012 - 08/2003
5	Hematologic Neoplasms (Hematological Malignancy) 06/2022 - 06/2008
5	Typical Teratoid Rhabdoid Tumor 01/2022 - 06/2011
5	Leukemia 01/2021 - 03/2004
5	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2018 - 12/2007
5	Chromosome Aberrations (Chromosome Abnormalities) 08/2010 - 03/2002
4	Carcinogenesis 08/2018 - 10/2003
3	T-Cell Prolymphocytic Leukemia (Leukemia, T Cell, Chronic) 01/2022 - 09/2009
3	Obesity 01/2022 - 10/2014
3	Androgen-Insensitivity Syndrome (Testicular Feminization) 12/2018 - 01/2013
3	Pathologic Complete Response 09/2014 - 12/2009
3	Non-Hodgkin Lymphoma (Lymphosarcoma) 03/2013 - 06/2003
3	Brain Neoplasms (Brain Tumor) 02/2013 - 10/2003
2	Body Weight (Weight, Body) 07/2022 - 08/2021
2	Non-alcoholic Fatty Liver Disease 01/2022 - 08/2013
2	Glioma (Gliomas) 01/2022 - 10/2003
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2017
2	Disease Progression 12/2021 - 02/2011
2	Residual Neoplasm 01/2021 - 03/2006
2	Glioblastoma (Glioblastoma Multiforme) 01/2017 - 10/2003
2	Multiple Myeloma 04/2015 - 11/2007
2	Neoplasm Metastasis (Metastasis) 09/2014 - 05/2012
2	Uniparental Disomy 06/2012 - 02/2010
2	Chromosome Breakage 11/2011 - 02/2010
2	Breast Neoplasms (Breast Cancer) 01/2007 - 12/2004
1	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 07/2022
1	Hepatomegaly 07/2022
1	Hypertriglyceridemia 07/2022
1	Dyslipidemias (Dyslipidemia) 01/2022
1	Li-Fraumeni Syndrome 01/2022
1	Central Nervous System Neoplasms 01/2022

Drug/Important Bio-Agent (IBA)

36	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2002
17	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 05/2004
14	Biological ProductsIBA 12/2021 - 06/2006
12	Transcription Factors (Transcription Factor)IBA 01/2021 - 04/2007
11	Immunoglobulins (Immunoglobulin)IBA 10/2018 - 03/2002
9	NF-kappa B (NF-kB)IBA 10/2010 - 04/2006
8	RNA (Ribonucleic Acid)IBA 12/2021 - 06/2006
8	Anaplastic Lymphoma KinaseIBA 10/2021 - 10/2003
8	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 01/2020 - 06/2003
8	Cyclin D1IBA 01/2019 - 12/2005
8	hydrogen sulfite (bisulfite)IBA 03/2016 - 01/2011
7	Biomarkers (Surrogate Marker)IBA 06/2022 - 01/2007
7	Messenger RNA (mRNA)IBA 01/2020 - 12/2004
7	CyclinsIBA 01/2019 - 12/2005
6	MicroRNAs (MicroRNA)IBA 01/2022 - 03/2009
6	ChromatinIBA 01/2018 - 11/2013
6	ParaffinIBA 11/2015 - 05/2006
5	Formaldehyde (Formol)FDA Link 11/2015 - 02/2013
4	Histones (Histone)IBA 04/2022 - 08/2006
4	IgKIBA 01/2013 - 03/2002
3	Insulin (Novolin)FDA Link 07/2022 - 08/2013
3	NucleotidesIBA 01/2021 - 01/2018
3	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2019 - 03/2004
3	Androgen Receptors (Androgen Receptor)IBA 12/2018 - 01/2013
3	Rituximab (Mabthera)FDA Link 11/2015 - 09/2009
2	Long Noncoding RNAIBA 06/2022 - 09/2015
2	LeptinIBA 01/2022 - 08/2021
2	SMARCB1 ProteinIBA 01/2021 - 09/2014
2	Protein Isoforms (Isoforms)IBA 01/2021 - 09/2009
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2020 - 11/2010
2	AndrogensIBA 12/2018 - 07/2009
2	Phosphotransferases (Kinase)IBA 01/2016 - 03/2004
2	AnthracyclinesIBA 11/2015 - 01/2007
2	Nonsense Codon (Nonsense Mutation)IBA 06/2011 - 02/2010
2	Adenosine Triphosphatases (ATPase)IBA 06/2011 - 02/2010
2	OligonucleotidesIBA 07/2010 - 09/2008
2	Cytokine Receptors (Cytokine Receptor)IBA 07/2010 - 09/2009
2	Macrophage Colony-Stimulating FactorIBA 05/2010 - 06/2008
2	Co-Repressor ProteinsIBA 05/2010 - 06/2008
2	NF-KappaB Inhibitor alphaIBA 01/2010 - 09/2009
2	AntigensIBA 11/2007 - 08/2002
2	TNF Receptor-Associated Factor 2 (TRAF2)IBA 04/2006 - 04/2005
2	Antigen Receptors (Antigen Receptor)IBA 02/2005 - 03/2004
1	Blood Glucose (Blood Sugar)IBA 07/2022
1	metreleptinIBA 07/2022
1	Histone DemethylasesIBA 04/2022
1	MelanocortinsIBA 01/2022
1	Basic Helix-Loop-Helix Transcription FactorsIBA 01/2022
1	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2021
1	Histocompatibility Antigens Class IIBA 12/2021
1	Ligases (Synthetase)IBA 12/2021

Therapy/Procedure

18	Therapeutics 12/2021 - 03/2006
5	Drug Therapy (Chemotherapy) 11/2015 - 01/2007
3	Ligation 01/2018 - 09/2010
2	Aftercare (After-Treatment) 01/2019 - 03/2004
2	Bariatric Surgery 10/2014 - 08/2013
1	Immunotherapy 06/2022